The Receipt
- 01Plausible and gentle; the receipt is mostly manufacturer data.
Education, not a diagnosis. If something changes quickly, hurts, bleeds, or worries you, see a dermatologist.
Ingredient Receipt · Peptides
Matrixyl 3000 (palmitoyl tripeptide-1 + palmitoyl tetrapeptide-7)
INCI: Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7
Matrixyl 3000 pairs two signal peptides aimed at collagen and inflammation. Popular in serums, with mostly manufacturer data. What to expect.
- Lines & firmness
01 · In plain English
Matrixyl 3000 is a two-peptide blend found in many multi-peptide serums. Searches for it, especially with Argireline, have jumped this year.
02 · What it does
Palmitoyl tripeptide-1 is a collagen-fragment signal peptide; palmitoyl tetrapeptide-7 is designed to calm inflammatory signals that break collagen down. Reviews of matrikine-style ingredients describe promising lab data and small clinical studies, many from ingredient makers.
03 · Who it’s for
- People already using sunscreen who want a gentle extra for fine lines.
04 · What the evidence says
- Fine lines and firmness over weeks.limited evidence
05 · Insufficient evidence
- Independent controlled trials of the blend.
- Benefits over palmitoyl pentapeptide-4.
06 · How to use it
- Once or twice daily in a serum, before moisturizer.
07 · Pairs well / go carefully
Pairs well with
- Argireline, hyaluronic acid, retinoids.
Go carefully with
- Strong acids in the same step.
Sources (3)
- Aldag C, Nogueira Teixeira D, Leventhal PS. Skin rejuvenation using cosmetic products containing growth factors, cytokines, and matrikines: a review of the literature. Clin Cosmet Investig Dermatol. 2016.
- Gorouhi F, Maibach HI. Role of topical peptides in preventing or treating aged skin. Int J Cosmet Sci. 2009.
- Errante F, et al. Cosmeceutical peptides in the framework of sustainable wellness economy. Front Chem. 2020.